Using BackBlaze with a NAS

I have a Mac Mini and a Windows 11 laptop. I want to set up a NAS to serve as storage for each machine.
Can BackBlaze connect directly to my NAS? Or does it have to connect to one of my devices?

Backblaze can backup NAS directly (they support Synology, QNAP, TrueNAS and Jellyfish natively), but it is a business plan. They claim to be half the price of AWS S3 storage.