There was discussion early in episode 561 about home office deductions. The Federal law actually changed. Unreimbursed employee business expenses, which sometimes included a home office, are no longer deductible for most individuals since tax year 2018. They may however still be deductible on state returns. The home office is still available on Schedule C (self employed businesses).
Disclaimer: This is not to be construed as tax advice and you should consult a professional with any questions.